Different products depending on your application
Flash Therapeutics offers two lentiviral vector delivery system and two qualities of vectors depending on your applications:
1. Integrative lentiviral vector (iLV) :
- Start quality (>107 IG/ml) for Research-grade vectors
- Very high level of transduction on permissive and “hard-to-transfect” immortalized cell lines
The Start batch is dedicated to screen and select the best vector candidates.
- Premium quality (>109 IG/ml) for Research-grade to GMP-grade vectors
- Very high level of transduction on primary & stem cells
- No cell damage thanks to the low impurity content
- Safe and clinically suitable delivery without inducing toxicity or immunogenicity
- In vivo genetic transfer
The Premium batch is dedicated to in vitro or ex vivo approaches, in vivo gene therapy, transgenesis or direct tissue injection experiments.
| Bacth type | Volume (mL) | Titre (IG/mL) | PP/IG |
|---|---|---|---|
| Start | 1-5 | >107 | <1000 |
| Premium | 1-60 | >109 | <300 |
Titre (IG/mL) : Number of lentiviral functional particles leading to integration of vector DNA into the host genome.
PP/IG ratio : Gives a measure of the lentiviral batch quality by discriminating the non functional physical particles (PP) from the functional particles.
2. Biological RNA delivery technology (non-integrative LentiFlash) :
- Start quality (>109 PP/ml) for Research-grade vectors
- Very high level of transduction on permissive and “hard-to-transfect” immortalized cell lines
- Premium quality (>1011 PP/ml) for Research-grade to GMP-grade vectors
- Very high level of transduction on primary & stem cells
- No cell damage thanks to the high purity level
- In vivo, in vitro and ex vivo cell transduction
The Premium batch is dedicated to in vitro or ex vivo approaches, in vivo gene therapy, or direct tissue injection experiments.
| Bacth type | Volume (mL) | Titre (PP/mL) |
|---|---|---|
| Start | 1-5 | >109 |
| Premium | 1-60 | >1011 |
Titre (PP/mL) : Number of physical p24 particles per mL.
High quality lentiviral solutions since 2005
With a strong know-how in lentiviral vector production and a robust bioproduction process, Flash Therapeutics has produced over 9000 lentiviral vector batches for scientists all over the world.